Anthony O.
You can connect different CRMs per table. Clay works in a column format and row format.
For eg, you have Table 1 which is bifurcated between two clients/use cases. In one column you can connect CRM 1 and have the run conditions for it. On the similar table, you can create column two which CRM 2 and have run conditions applied for that one.
How you structure your data in this regard would be the key for it.