It鈥檚 easier to get going. The analogy I鈥檝e seen used for this is apple vs android. Instantly has everything you need out of the box to run campaigns at scale. Smartlead requires a bit more tinkering to set things up
It鈥檚 best to have a dedicated sending tool while keeping apollo for list building only. both instantly and smartlead are great. If you鈥檙e going to utilize apis heavily, then I鈥檇 go with smartlead, if not instantly works.