How to Handle Duplicates in Clay & Instantly for Efficient Cold Outreach

Hey Clay team- I’m new to Clay (and cold outreach) and am looking for guidance/best practices on how to handle lists. I’m currently building lists by searching for keywords. The challenge is that keyword searches often generate the same contact/company using different search terms. My question is how should I handle duplicates? If I do a search today and email those prospects, I don’t want to do a search next week and accidentally re-email (or pay to enrich a second time) the same prospects. I’m using Clay together with Instantly. Do most people use a master database outside of Clay for the lists or can Clay help keep my lists organized?