Optimizing Ocean.io Enrichment for Lookalike Audience Expansion

I'm using the Ocean.io enrichment to build a lookalike audience. I ran it once, and now I want to re-run to find more companies - if I simply change the setting in the existing enrichment column, will I be duplicating the efforts from the first time it ran? if so, is there a better way to set up a "progressive expansion" (eg. more companies without duplicating the originals + wasting credits)