Using Webhooks and Auto-Dedupe to Update Records in a Database

We're trying to use webooks and auto-dedupe to update records in a table. Is that possible? I want to run two events to a table via webhook:

Not every lead will submit the email, but every lead will submit the domain. I want the second webhook to override the first webhook using auto-dedupe so that in the case that the lead submits the domain and email, we have those two data points in our table as a single record instead of two records, one with domain and one with email and domain. Right now auto-dedupe simply ignores the second webhook.